Biophysical basis for monophasic action potential
نویسندگان
چکیده
منابع مشابه
Cellular basis for the monophasic action potential. Which electrode is the recording electrode?
BACKGROUND The cellular basis for the monophasic action potential (MAP) has long been a matter of debate. At the center of the controversy is the issue as to which of the two electrodes is the recording electrode and which is the indifferent electrode. The present study is designed to address this issue. METHODS Transmembrane action potentials (TAPs) and either intramural MAPs or contact (Fra...
متن کاملCellular basis for the monophasic action potential . Which electrode is the recording electrode ? Masahiko Kondo
Background: The cellular basis for the monophasic action potential (MAP) has long been a matter of debate. At the center of the controversy is the issue as to which of the two electrodes is the recording electrode and which is the indifferent electrode. The present study is designed to address this issue. Methods: Transmembrane action potentials (TAPs) and either intramural MAPs or contact (Fra...
متن کاملBiophysical Basis for Three Distinct Dynamical Mechanisms of Action Potential Initiation
Transduction of graded synaptic input into trains of all-or-none action potentials (spikes) is a crucial step in neural coding. Hodgkin identified three classes of neurons with qualitatively different analog-to-digital transduction properties. Despite widespread use of this classification scheme, a generalizable explanation of its biophysical basis has not been described. We recorded from spina...
متن کاملMonophasic action potential duration during programmed electrical stimulation.
UNLABELLED To examine changes in monophasic action potential duration (APD) with a pacing protocol similar to that used during electrophysiological testing, action potentials were recorded in vivo from the left ventricular apical endocardium of 12 normal mongrel dogs. The atrioventricular node was ablated and the dogs paced from the anterior right ventricle at a baseline cycle length of 1000 ms...
متن کاملMonophasic Action Potential Morphology in the Human Heart
Background. Recent studies examining mechanisms of defibrillation have focused on prolongation of graded cellular response duration during refractory period stimulation. This mechanism assumes that defibrillation shocks interact with ventricular cells during the process of repolarization. Methods and Results. To test this assumption, we examined monophasic action potentials (MAPs) from 171 epis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2005
ISSN: 0008-6363
DOI: 10.1016/j.cardiores.2004.12.018